Episode 2

A transcriptional cofactor‐mediated dependency module - Ep 2.2

In this newest podcast episode, Dr Charles de Bock hosts Dr Thomas Mercher and Dr Alexandre Fagnan. This episode is based on their recent paper, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program”, highlighting ETO2 activated gene transcription and how this affects erythroleukemia. The discussion traces the journey from part of Dr Fagnan’s PhD project (2022 EHA Junior Grant awardee), the findings in the paper and what may lie beyond.

This episode is also available on our YouTube channel .

Listen and enjoy casual, insightful discussions about #hematology research.

You can find the referenced article, “The ETO2 transcriptional co-factor maintains acute leukemia by driving a MYB/EP300-dependent stemness program” in full and open access, here on the HemaSphere website.

Next Episode All Episodes Previous Episode

About the Podcast

Show artwork for HemaSphere Podcast
HemaSphere Podcast
The HemaSphere Podcast focuses on casual and insightful discussions about select HemaSphere publications and hematology research. Listen to the stories behind the papers.

Listen for free

About your hosts

Profile picture for HemaSphere Journal

HemaSphere Journal

Listen and enjoy casual, insightful discussions about #hematology research.
Profile picture for European Hematology Association

European Hematology Association

The European Hematology Association promotes excellence in patient care, research, and education in hematology. We serve medical professionals, researchers, and scientists with an active interest in hematology. We are proud to be the largest European-based organization connecting hematologists worldwide to support career development and research, harmonize hematology education, and advocate for hematologists and hematology