Episode 6

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Published on:

1st Sep 2025

Tackling NUP98 Rearranged AML in Pediatric Oncology - Episode 3.5

Host Dr Charles de Bock speaks with Prof Michel Zwaan and Prof Olaf Heidenreich, co-authors from the 2025 HemaSphere Award - Top Cited: Biology paper, "The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML." The conversation delves into the complexities of #AML, particularly focusing on NUP98 rearranged AML and the therapeutic potential of Menin inhibitors. The discussion highlights the challenges in treating this aggressive form of leukemia, the mechanisms of menin inhibitors, and the importance of combining therapies to improve patient outcomes. 

Season 3, Episode 5: Tackling NUP98 Rearranged AML in Pediatric Oncology, is on our website and all major podcast platforms. Listen and enjoy casual, insightful discussions about #hematology research. 

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About the Podcast

HemaSphere Podcast
The HemaSphere Podcast focuses on casual and insightful discussions about select HemaSphere publications and hematology research. Listen to the stories behind the papers.
HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinical research in hematology. We are pleased to introduce our new podcast series where our host and guest speakers exchange ideas about select HemaSphere publications. Spend some time with us and enjoy casual and insightful discussions about hematology research. Listen to the stories behind the papers. HemaSphere is always accessible; our full range of open access publications is available at www.hemaspherejournal.com.

About your host

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European Hematology Association

The European Hematology Association promotes excellence in patient care, research, and education in hematology. We serve medical professionals, researchers, and scientists with an active interest in hematology. We are proud to be the largest European-based organization connecting hematologists worldwide to support career development and research, harmonize hematology education, and advocate for hematologists and hematology